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RFdiffusion

UW/Baker Lab · 2023 · Science/Biology · USA

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A to Z

A · App
No
B · Built By
UW/Baker Lab
C · CEO & Politics
N/A (academic research) — No public partisan activity documented
D · Date
2023
E · Expertise
Intermediate+
F · Free Tier
Yes
G · Generates
Text only
H · Deployment
Cloud + Local (open weights)
I · Inputs
Text
J · Jurisdiction
USA
K · Key Staffers
Joseph L. Watson (Co-lead author), David Juergens (Co-lead author), Nathaniel R. Bennett (Co-lead author), Brian L. Trippe (Co-lead author), Jason Yim (Co-lead author), Helen E. Eisenach (Co-lead author), Woody Ahern (Co-lead author), David Baker (Senior author)
L · Languages
English-primary
M · Model Type
Science/Biology
N · Safety Issues
None reported
O · Open Source
Yes — open weights
P · Pricing
Free (open source, BSD; covers code and weights)
Q · AIDb Rating
[UNKNOWN]
R · What Makes It Special
RFdiffusion, an open-source diffusion method for generating protein structures with or without conditioning information such as a motif or target; it handles motif scaffolding, unconditional and symmetric (cyclic, dihedral and tetrahedral) generation, symmetric motif scaffolding, binder design and design diversification through partial diffusion.
S · Stock / Status
Research / open-source project
T · Training Cutoff
[UNKNOWN]
U · Users
[UNKNOWN]
V · Voice Chat
No
W · Weights
Downloadable
X · X Handle
[UNKNOWN]
Y · Year Founded
[UNKNOWN]
Z · Bottom Line
Open-weights Science/Biology from UW/Baker Lab, released 2023.

Data completeness 81% · Last verified 2026-05-12 · Primary source ↗

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“RFdiffusion.” AIDb — The AI Database. Verified 2026-05-12. https://theaidatabase.com/m/rfdiffusion.html