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Arc Institute Evo 2

Arc Institute · 2025 · Science/Biology · USA

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A to Z

A · App
No
B · Built By
Arc Institute
C · CEO & Politics
[UNKNOWN]
D · Date
2025
E · Expertise
Intermediate+
F · Free Tier
Yes
G · Generates
Text only
H · Deployment
Cloud + Local (open weights)
I · Inputs
Text
J · Jurisdiction
USA
K · Key Staffers
Garyk Brixi (Lead author), Patrick D. Hsu (Senior author), Brian L. Hie (Senior author)
L · Languages
English-primary
M · Model Type
Science/Biology
N · Safety Issues
None reported
O · Open Source
Yes — open weights
P · Pricing
Free (open weights, Apache 2.0)
Q · AIDb Rating
5/10 · AIDb v2.0 (rule-based): Capability 4/10 · Currency 4/10 · Access 8/10 · Significance 4/10 → 4.60
R · What Makes It Special
Evo 2, Arc Institute's open DNA language model, built with NVIDIA and researchers from Stanford, UC Berkeley and UCSF: trained on over 9.3 trillion nucleotides from over 128,000 genomes across all three domains of life, in 40B and 7B versions that read up to 1 million nucleotides with the StripedHyena 2 architecture. Arc reports over 90% accuracy in sorting benign from potentially pathogenic BRCA1 variants; human-infecting pathogens were left out of training, and data, code and weights are open.
S · Stock / Status
Non-profit research institute
T · Training Cutoff
[UNKNOWN]
U · Users
[UNKNOWN]
V · Voice Chat
No
W · Weights
Downloadable
X · X Handle
@arc_institute
Y · Year Founded
[UNKNOWN]
Z · Bottom Line
Open-weights Science/Biology from Arc Institute, released 2025.

Data completeness 85% · Last verified 2026-06-11 · Primary source ↗

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“Arc Institute Evo 2.” AIDb — The AI Database. Verified 2026-06-11. https://theaidatabase.com/m/arc-institute-evo-2.html